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This video presents a detailed review and analysis of the following preprint: Lanna, A., et al. (2025). CD4⁺ T cells confer transplantable rejuvenation via Rivers of telomeres. bioRxiv. https://doi.org/10.1101/2025.11.14.688504 The paper is authored by researchers from Sentcell UK Laboratories, the University of Oxford, and University College London, with Professor Alessio Lanna as senior author. This video covers the key findings of the paper, including: - The discovery of "telomere Rivers" — extracellular vesicles released by CD4⁺ T cells enriched in stemness factors and depleted of glycolytic enzymes - The mechanism of telomere transfer from antigen-presenting cells (APCs) to T cells via fatty acid oxidation at the immune synapse - Evidence of rejuvenation of senescent tissues across multiple organs in aged mice - Lifespan extension of approximately 17 months (median) in aged mice, with several animals surviving to nearly five years - The development of "Artificial Rivers" that b
Dr. Alessio Lanna discusses his breakthrough research showing 17-month median lifespan extension in mice through "rivers of telomeres" and why human trials start in 2025. If you would like to support our channel please consider joining our Patreon https://patreon.com/ModernHealthspan ~~~~~~~~~~~~~~ *Renue By Science* (10% off: MHS) https://tinyurl.com/bdew4bfs NMN Powder • Lipo NR *BiOptimizers* (15% off: MHBIO) https://bit.ly/47VAa8f - Magnesium Breakthrough *Stemregen* (15% off: MODERN) *US only* https://tinyurl.com/45z968yr *Wellness Extract* (10% off: MODERNWE) http://wellnessextract.com/RICHARDWE Geranylgeraniol • Vit E *AX3 Life* (20% off: MODERN20) https://tinyurl.com/2t3w26nw - Astaxanthin *Oxford Healthspan* (15% off: MHS) https://tinyurl.com/hrxfnzpn - Spermidine *Seeking Health* (10% off: Richard10) https://crrnt.app/SEEK/-dm0MyrQ, Histamine Nutrients https://crrnt.app/SEEK/EpM7paAO ProHealth* (15% off: MODERN) https://prohealth.pxf.io/aObQRR NMNH 500mg These are affili
A potential functional cure for HIV could be just months away from human trials. Dr. Lanna reveals how her company Sentcell is using cellular rejuvenation to eliminate HIV reservoirs—and the surprising anti-aging benefits that come with it. Some links are affiliate links so we will earn a commission when they are used to purchase products. --------------------- If you would like to support our channel please consider joining our Patreon https://patreon.com/ModernHealthspan *Renue By Science* (10% off: MHS) https://tinyurl.com/bdew4bfs NMN Powder • Lipo NR *BiOptimizers* (15% off: Modern10) https://bit.ly/42OqRVW - Magnesium Breakthrough *Stemregen* (15% off: MODERN) *US only* https://tinyurl.com/45z968yr *Qualia* (15% off: MODERN) Senolytic: https://tinyurl.com/22t9thrn • Mind: https://tinyurl.com/5hatj2t2 *Life Extension* ($10 off $50 order) NAC: https://tinyurl.com/vzvbde99 • Ergothioneine 25mg https://tinyurl.com/48h2bnst *NOVOS* ($5 off: 5OFFMHS24) https://novos.sjv.io/QyWP7o,
Is it possible to rejuvenate the immune system as we age? In this episode, Dr. Alessio Lanna breaks down the science of immune aging, focusing on the critical role of T cells, telomere shortening, and senescence. He explains how T cells lose their effectiveness over time—and shares emerging research on how intercellular telomere transfer and the ESMAC complex may help reverse immune senescence. Learn how pharmacological interventions could unlock new possibilities for health, longevity, and immune rejuvenation. Learn more about Dr. Alessio Lanna: https://sentcell.life/team/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/ - 🎁 Special offers from our podcast guests: 🧬 Telo-Vital (Dr. Bill Andrews) – 55% Off: Get your first bottle for $49 with free shipping to US, UK, Canada, Mexico, Australia, New
Here Dr Lanna talks about his work in rejuvenating the immune system by rescuing senescent T--cells. Some links are affiliate links so we will earn a commission when they are used to purchase products. If you would like to support our channel please consider joining our Patreon https://patreon.com/ModernHealthspan Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) n1o1 Nitric Oxide 10% discount with code Modern https://tinyurl.com/3esakm4s n1o1 Nitric Oxide Lozenges https://tinyurl.com/yh4rrtht Age-Defiance Face Cream https://tinyurl.com/4zr959zh Renue By Science 10% discount code MHS: https://tinyurl.com/bdew4bfs NMN Powder https://tinyurl.com/syc7rwkh DoNotAge 10% discount code MHS https://tinyurl.com/6dbvhv87 NMN https://tinyurl.com/wyzj2f3d CaAKG https://tinyurl.com/2h79stt2 BiOptimizers Magnesium Breakthough 10% Code Modern10 https://bioptimizers.com/modern Wellness Extract 10% discount Code MODERNWE Gerany
Alessio Lanna, fondatore della startup Sentcell, ripercorre le vare fasi della sua formazione prestigiosa, nazionale e internazionale, sottolineando però che i titoli accademici sono solo un primo passo: "Bisogna trovare forti motivazioni dentro di sé e credere nella possibilità di cambiare in meglio la vita delle persone. Gli studi sulla longevità sono la nuova frontiera"
70% Lifespan Extension: Immune-Derived "Telomere Rivers"—A Transferable Youth Signal? - News - Rapamycin Longevity News Rapamycin Longevity News 70% Lifespan Extension: Immune-Derived "Telomere Rivers"—A Transferable Youth Signal? News RapAdmin January 27, 2026, 9:29am #1 RiversOTelomeres 2752×1536 273 KB A research team led by Prof. Alessio Lanna (CEO of Sentcell ) has released a provocative manuscript describing a new “fluid” organ of the immune system: “Telomere Rivers.” Building on their previous discovery that antigen-presenting cells (APCs) donate telomeres to T cells … he placebo group), the test group they have been aged to 20 months as they only apply the vesicles at 20 months… Maybe they expected the mice to live to at least 20 months and they didn’t. The other experiment uses 20 month old mice in both experiments. 1 Like KarlT January 28, 2026, 1:38am #5 Nice to know we’re all gonna live an extra 50 years. 1 Like RapAdmin January 28, 2026, 1:42am #6 Screenshot 2026-01-27 at 5.41.44 PM 984×900 68.2 KB 3 Likes John_Loverich January 28, 20 … he placebo group), the test group they have been aged to 20 months as they only apply the vesicles at 20 months… Maybe they expected the mice to live to at least 20 months and they didn’t. The other experiment uses 20 month old mice in both experiments. Andrew Steele is spot on here, and your logic is completely off the mark. Think about it: if the experimental group only gets injected at 20 months of age, those mice are already survivors who successfully made it to that 20-m
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UK Leadership in Global Health Innovation | Matthew Lindley posted on the topic | LinkedIn LinkedIn respects your privacy LinkedIn and 3rd parties use essential and non-essential cookies to provide, secure, analyze and improve our Services, and to show you relevant ads (including professional and job ads ) on and off LinkedIn. Learn more in our Cookie Policy . Select Accept to consent or Reject to decline non-essential cookies for this use. You can update your choices at any time in your settings . Accept Reject Agree & Join LinkedIn By clicking Continue to join or sign in, you agree to Linked … pult the global HIV response to the finish line. But this can only happen if we fund the critical international institutions that can make sure the drugs and support gets to people affected by HIV everywhere around the world. The Global Fund to Fight AIDS, TB and Malaria is the main global mechanism for getting funding and services where they are needed and the UK has recently made a significant funding commitment to it. But there are three other small but mighty institutions … are fundamental to ensure the global HIV response works properly - Robert Carr Fund, UNAIDS and Unitaid. In January the UK will confirm its commitment to these three organisations. We have joined a powerful alliance with The Independent, UK HIV organisations, and MPs from across the political spectrum, to write a letter to the Prime Minister Keir Starmer to make sure the UK delivers for these organisations and champions the end of the aids pandemic by 2030 wherever possible. … , and treatment. 📄 Detailed tender information: 🔗 https://lnkd.in/daNbf_Jb 🗓 Application deadline: 04 February 2026, 15:26 (Bishkek time) 📧 Tender-related inquiries: [email protected] 2 Like Comment Share Copy LinkedIn Facebook X To view or add a comment, sign in Emma Khaukha 5mo Report this post Viral load monitoring. The Ministry of Health/AIDS Control Programme (MOH/ACP) recommends Viral Load (VL) monitoring as a gold standard for assessing the effectiveness of antiretro … ct on Health Outcomes Key Challenges in Women's Health Innovation Global Health Fund Partnerships Explore content categories Career Productivity Finance Soft Skills & Emotional Intelligence Project Management Education Technology Leadership Ecommerce User Experience Recruitment & HR Customer Experience Real Estate Marketing Sales Retail &
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Spain triples women’s health research funding Latest News Opinion Insight Events Newsletter sign up Awards entry Contact us Advertise Podcast Connect with us FemTech World Spain triples women’s health research funding Latest News Opinion Insight Events Newsletter sign up Awards entry Contact us Advertise Podcast Menopause Spain triples women’s health research funding Published 5 days ago on June 18, 2026 By News Desk Spain will triple annual women’s health research funding to €18m under a programme focused on discrimination in medical research. Spain’s Ministry of Science will increase investm … ealed News 4 weeks ago Three menopause innovators shortlisted for Femtech World Award Copyright © 2025 Aspect Health Media Ltd. All Rights Reserved. We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept All”, you consent to the use of ALL the cookies. However, you may visit "Cookie Settings" to provide a controlled consent. Cookie Settings Accept All Manage consent Close Privacy Overview T
Telomere Rivers Extend Lifespan in Mice Study | Joao Pedro de Magalhaes posted on the topic | LinkedIn LinkedIn respects your privacy LinkedIn and 3rd parties use essential and non-essential cookies to provide, secure, analyze and improve our Services, and to show you relevant ads (including professional and job ads ) on and off LinkedIn. Learn more in our Cookie Policy . Select Accept to consent or Reject to decline non-essential cookies for this use. You can update your choices at any time in your settings . Accept Reject Agree & Join LinkedIn By clicking Continue to join or sign in, you agr
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Sentcell | Top Biotech Company in UK - 2023 --> --> CLOSE Specials I agree We use cookies on this website to enhance your user experience. By clicking any link on this page you are giving your consent for us to set cookies. More info Welcome to Life Science Review! We use cookies and similar technologies to enhance your experience on our website and to provide personalized content and advertisements. By clicking "Accept," you agree to the use of these technologies as described below. You can manage your choices or withdraw consent at any time by visiting our Privacy Policy page. Essential Cook … f DOS extends an animal’s lifespan up to the equivalent of 120 human years. Its application is also against long-term conditions that specifically affect T-cells, such as HIV. DOS-based approach not only rejuvenates the T cells but the entire organism, and when combined with vaccination, can provide a stronger immune response that allows for long-lasting, quality protection. Sentcell has proved that DOS, when combined with clinically approved influenza and COVID-19 vaccinatio … he DOS and NOS can be combined. Once a person is rejuvenated using DOS, the NOS application can sustain the rejuvenation results. Molecules that promote sMAC formation, like patent-pending Mobiliser Of sMAC (MOS), have also been developed. The reason for sMAC stimulation is that before the senescence of T cells, there is a massive expansion of lymphocytes, which effectively control aggressive cancers and other life-threatening conditions. Under certain conditions, the presenc … ay that proved to be 30 times more powerful and faster than Telomerase, a Nobel Prize winning discovery and enzyme that replenishes the ends of chromosomes containing telomeres as they typically shorten with cell division. Telomere transfer entails transferring telomeres from antigen-presenting cells via vesicles to T cells. The transferred telomeres fuse and merge with the chromosome ends to elongate it inside the T cell. This way, the T cells are fully protected from senesc
--> Venue Boston Marriott Peabody, MA Dates November 16-18, 2026 Call +1-659-226-7797 --> Home Home Page 01 Home Page 02 Home Page 03 Header Styles Header Style 01 Header Style 02 Header Style 03 --> About About Vaccines Summit-2026 Vaccines Summit-2024 Vaccines Summit-2023 Vaccines Summit-2022 Vaccines Summit-2021 2023 Photo Gallery Contact Pages About About Us Buy Ticket Gallery Testimonials Comming Soon Schedule Schedule 01 Schedule 02 Schedule 03 Schedule Detail FAQ's Speaker Speaker Speaker Detail Testimonials Comming Soon Contact us Blog Blog Classic Blog Grid Blog Single Error 404 --> K … 18, 2026 Dates [email protected] Mail to us +1-659-226-7797 Call Contact Us Submit Now Boston Marriott Peabody, MA Venue November 16-18, 2026 Dates [email protected] Mail to us +1-659-226-7797 Call Speakers Home Speakers --> Alessio Lanna Ph.D. Speciality: Ph.D. Company: University College London, Sentcell ltd (UK), CEO Designation: Professore Ordinario Personal Information Prof. Alessio Lanna, Ph.D. is the Founder of Sentcell. He obtained his Ph.D. from the Universit
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Awakening intracellular immunity for functional HIV cure | bioRxiv Skip to main content Home About Submit ALERTS / RSS Search for this keyword Advanced Search New Results Awakening intracellular immunity for functional HIV cure View ORCID Profile Alessio Lanna , Federica Rinaldi , Christof Stingone doi: https://doi.org/10.64898/2026.01.04.697570 Alessio Lanna 1 University College London, Division of Medicine , London. United Kingdom 2 Monte-Carlo, Principality of Monaco . Monaco 3 Sentcell UK laboratories, Tuscany Life Sciences , GSK Vaccine Campus, Siena. Italy Find this author on Google Scho
Detection of Telomere Transfer at Immunological Synapse Detection of Telomere Transfer at Immunological Synapse Methods Mol Biol . 2023:2654:251-261. doi: 10.1007/978-1-0716-3135-5_16. Authors Alessio Lanna 1 , Clara D'Ambra 2 Affiliations 1 Sentcell UK laboratories, Rome, Italy. [email protected]. 2 Sentcell UK laboratories, Rome, Italy. PMID: 37106187 DOI: 10.1007/978-1-0716-3135-5_16 Abstract Eukaryotes solve the DNA-end replication problem synthesizing hexameric chromosome ends known as telomeres. Recent studies have uncovered unexpected functions of telo
Team - Sentcell® About Team Milestones Publications and Updates Contact Platform Pipeline Team Rejuvenation, Resilience, and Rationalism. Founder and CEO Prof. Alessio Lanna, Ph.D. Prof. Alessio Lanna, Ph.D. is the Founder of Sentcell. He obtained his Ph.D. from the University College London on Medical Research Council-Ph.D. studentship (2011-2016) and then continued as a Sir Henry Wellcome Trust Post-Doctoral Fellow at the University of Oxford (2016-2019). He currently holds an Honorary Professorship at UCL in recognition of paradigm shifting research in the field of cellular ageing and T lym
Milestones - Sentcell® About Team Milestones Publications and Updates Contact Platform Pipeline Milestones Expansion, Elaboration, and Exemplification. July 2014 Discovery of a link between T cell ageing and metabolism by the Founder (Lanna et al. Nature Immunology 2014) January 2017 Identification of sMAC (Sestrin MAP kinase activation complex) as a multi-druggable longevity target (Lanna et al. Nature Immunology 2017) May 2019 Establishment of Sentcell Ltd to translate the sMAC discovery into longevity (rejuvenating and anti-ageing) therapies following seed investment April 2021 Series A fun … therapies following seed investment April 2021 Series A funding to support IMPD application for first in human (FIH) DOS46L rejuvenating program and sMAC pipeline expansion December 2021 International Patent Cooperation Treaty (PCT) filing for "Sestrin-MAP kinase complex inhibitors" describing synthesis of first in class disruptors of sMAC and their use to treat age-related diseases June 2022 Recognition of DOS as a new immune rejuvenating class by the Indian Health Authoriti
Please join us at Sentcell ! | Sentcell Ltd LinkedIn respects your privacy LinkedIn and 3rd parties use essential and non-essential cookies to provide, secure, analyze and improve our Services, and to show you relevant ads (including professional and job ads ) on and off LinkedIn. Learn more in our Cookie Policy . Select Accept to consent or Reject to decline non-essential cookies for this use. You can update your choices at any time in your settings . Accept Reject Agree & Join LinkedIn By clicking Continue to join or sign in, you agree to LinkedIn’s User Agreement , Privacy Policy , and Cook … passion in all areas of cell biology and immunology are strongly encouraged to apply. Research activities are in Rome, at Fondazione Santa Lucia. Please get in touch to discuss your next career step! The lab is world renowned for the discovery of immune senescence pathways (Lanna et al Nature Inmunology 2014; Lanna et al Nature Immunology 2017) and telomere transfer, a more powerful alternative to telomere extension than telomerase activation itself (Lanna et al Nature Cell
Sentcell | Top Biotech Company in UK-2023 | Professor Alessio Lanna Ph.D. LinkedIn respects your privacy LinkedIn and 3rd parties use essential and non-essential cookies to provide, secure, analyze and improve our Services, and to show you relevant ads (including professional and job ads ) on and off LinkedIn. Learn more in our Cookie Policy . Select Accept to consent or Reject to decline non-essential cookies for this use. You can update your choices at any time in your settings . Accept Reject Agree & Join LinkedIn By clicking Continue to join or sign in, you agree to LinkedIn’s User Agreeme
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PhD or Junior Postdoc Position in Immune Rejuvenation Research. – Scientific Bangladesh Skip to content Scientific Bangladesh Menu Home Article Interviews Scientific Publications Advertise with us Contact Us Register Login Register Login Menu Home About SB Editorial Articles Science, Policy & Development Research Management Digital Technology and Cyber security Environmental Sciences Food and Agricultural Sciences Health/ Medical/ Biomedical Sciences Funds/grants/awards Conference/organizational News Higher Studies/scholarships/Jobs Inspirational Scientists and Science Jobs Power an … ge of immune rejuvenation research, helping to shape the future of medicine. 🔹 Application Deadline: April 28, 2025 Click to Apply: Sentcell LTD looks forward to welcoming passionate scientists eager to drive innovation in cellular rejuvenation and immune restoration. Previous The Science & PINS Prize for Neuromodulation: Fostering Innovation in Neuroscience. Next Fully Funded PhD Scholarships at the University of Cambridge. Related Posts Research Scientists (multiple ro
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Femtech World Awards 2025: Winners revealed - FemTech World Latest News Opinion Insight Events Newsletter sign up Awards entry Contact us Advertise Podcast Connect with us FemTech World Femtech World Awards 2025: Winners revealed Latest News Opinion Insight Events Newsletter sign up Awards entry Contact us Advertise Podcast News Femtech World Awards 2025: Winners revealed Published 1 year ago on May 28, 2025 By News Desk Femtech World is delighted to reveal the winners of this year’s Femtech World Awards, sponsored by Planned Parenthood . The winning entries were announced on Wednesday afterno … merge with Breakthrough Victoria, also participated through its Alice Anderson Fund, which focuses on female founders. Amanda Andriano, founding partner at Admiralty Capital Group, said the gender health gap was a problem that should not be tolerated. She said: “Ovum combines mission, market timing and technical capability with an exceptional founder uniquely positioned to lead this movement, and we believe that creates the foundation for a company of global significance.” T … ealed News 4 weeks ago Three menopause innovators shortlisted for Femtech World Award Copyright © 2025 Aspect Health Media Ltd. All Rights Reserved. We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept All”, you consent to the use of ALL the cookies. However, you may visit "Cookie Settings" to provide a controlled consent. Cookie Settings Accept All Manage consent Close Privacy Overview T
Browse by Title Skip to main content Toggle navigation Login Search Home Scientific Program Browse by Title Home Browse by Title Browse by Title Type here to filter the list All A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # # 3rd and 4th Doses of Mrna Vaccines Broaden and Prolong Immune Responses to sars-cov-2 in Immunocompromised Patients with Immune-mediated Inflammatory Diseases Favorite Michelle W. Cheung – University of Toronto ### 1945802###Presenting Author###PhD Student###University of Toronto### Presenting Author: Michelle W. Cheung – University of Toronto ### A A … ndash; The University of Chicago ### she/her/hers Partner Program: Getting Your Application Off on the Right Foot: Receipt and Referral Sponsored By Favorite Thomas R. Esch, PhD – DAIT/NIAID/NIH/DHHS ### 542129###Speaker###Program Officer###DAIT/NIAID/NIH/DHHS### Speaker: Thomas R. Esch, PhD – DAIT/NIAID/NIH/DHHS ### @@@ Deborah Hodge, PhD – NIAID/NIH ### 2015383###Speaker###Program Officer###NIAID/NIH### Speaker: Deborah Hodge, PhD – NIAID/NIH … dash; Journal of Experimental Medicine (JEM) ### Partner Program: Lupus Insight Prize Award Ceremony and Luncheon Sponsored By Favorite Gary Koretzky, MD, PhD – Chair, Lupus Research Alliance Scientific Advisory Board; Cornell University ### 1664381###Speaker######Chair, Lupus Research Alliance Scientific Advisory Board; Cornell University### Speaker: Gary Koretzky, MD, PhD – Chair, Lupus Research Alliance Scientific Advisory Board; Cornell University ### @
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New trial aims to extend immune system lifespan Latest News Opinion Insight Events Newsletter sign up Awards entry Contact us Advertise Podcast Connect with us FemTech World New trial aims to extend immune system lifespan Latest News Opinion Insight Events Newsletter sign up Awards entry Contact us Advertise Podcast News New trial aims to extend immune system lifespan Published 5 days ago on June 18, 2026 By News Desk A first-in-human clinical trial of an immune rejuvenation therapy designed to restore the function of worn-out T cells is expected to begin later this year, building on research … merge with Breakthrough Victoria, also participated through its Alice Anderson Fund, which focuses on female founders. Amanda Andriano, founding partner at Admiralty Capital Group, said the gender health gap was a problem that should not be tolerated. She said: “Ovum combines mission, market timing and technical capability with an exceptional founder uniquely positioned to lead this movement, and we believe that creates the foundation for a company of global significance.” T … cking News 4 weeks ago Three menopause innovators shortlisted for Femtech World Award Copyright © 2025 Aspect Health Media Ltd. All Rights Reserved. We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept All”, you consent to the use of ALL the cookies. However, you may visit "Cookie Settings" to provide a controlled consent. Cookie Settings Accept All Manage consent Close Privacy Overview T
Podcast/ Noi, gli hacker dell’età:... - Massimo Cerofolini Facebook Log In Massimo Cerofolini's Post Massimo Cerofolini May 11 · Shared with Public Podcast/ Noi, gli hacker dell’età: così addestriamo le cellule a tornare giovani Topi anziani che tornano dritti e vitali come cuccioli. Cellule che si scambiano “pacchi di giovinezza” nel sangue. Un’unica iniezione sperimentale che sembra riaccendere il sistema immunitario come un computer dopo il reset. E' questa la direzione della ricerca scientifica più avanzata che cerca la strada per allungare la vita in salute. Con un pezzo d’Itali
This Therapy May Cure AIDS And… ‑ Modern Healthspan ‑ Apple Podcasts Rechercher Accueil Nouveautés Classements Rechercher 29 septembre 2025 55 min This Therapy May Cure AIDS And Extend Your Lifespan | Dr Alessio Lanna Modern Healthspan Lire A potential functional cure for HIV could be just months away from human trials. Dr. Lanna reveals how her company Sentcell is using cellular rejuvenation to eliminate HIV reservoirs—and the surprising anti-aging benefits that come with it. n this groundbreaking interview, Dr. Lanna, founder and CEO of Sentcell, explains how his team has developed a revolut
First human trial targets aging immune cells for healthier immunity Skip to content Menu Medical Home Life Sciences Home Become a Member Search Medical Home Life Sciences Home About Functional Food News Health A-Z Drugs Medical Devices Interviews White Papers More... MediKnowledge eBooks Posters Podcasts Videos Newsletters Health & Personal Care Contact Meet the Team Advertise Search Become a Member Top Health Categories Coronavirus Disease COVID-19 Diet & Nutrition Artificial Intelligence Allergies Alzheimer's & Dementia Arthritis & Rheumatology Breast Cancer Breastfeeding … nfidential information. Read the full Terms & Conditions . Provide Feedback Submit Cancel You might also like... × How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases
Apple Podcast：《Modern Healthspan》〈Rejuvenating the Immune System⋯〉 搜尋 首頁 新發現 熱門排行榜 搜尋 2025年2月12日 45 分鐘 Rejuvenating the Immune System to Extend Lifespan & Healthspan | Dr Alessio Lanna Interview Modern Healthspan 播放 Here Dr Lanna talks about his work in rejuvenating the immune system by rescuing senescent T--cells. 🌐Links in this video Sentcell website https://sentcell.life/ Some of Dr Lanna's published papers An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory https://pubmed.ncbi.nlm.nih.gov/36109671/ Rejuvenation driven repr
About - Sentcell® About Team Milestones Publications and Updates Contact Platform Pipeline About Sentcell is an exclusive NCE (New Chemical Entity) company that develops first in class human rejuvenating therapies by rational design focused on a single pathway: the sMAC. Rejuvenating drugs for renewed life Our vision is to implement fundamental medicine by a dual based approach to reverse the ageing clock at later points in life (rejuvenating drugs) or delaying it acting at an earlier one (anti-ageing drugs). To do this, we have been focusing on T cells, which themselves employ a variety of st
Publications and Updates - Sentcell® About Team Milestones Publications and Updates Contact Platform Pipeline Publications and Updates Science, Shift, and Synthesis 25 August 2022 Alessio and Sentcell Team discover intercellular telomere transfer at the immune synapse that rescues T cells from senescence. Read 19 July 2022 Successful meeting with UK MHRA to discuss upcoming IMPD DOS46L application for FIH immune rejuvenation Read Contact Sentcell® Go to contact Platform Pipeline About Team Milestones Publications and Updates Headquarter 607 Sloane Avenue SW3 3EL, London England United Kingdom
Pipeline - Sentcell® About Team Milestones Publications and Updates Contact Platform Pipeline Pipeline We investigate fundamental biology through an academic lens and with a business mindset Compounds Indication Discovery Pre-clinical Phase 1 Phase 2 Phase 3 Planned with: Planned with series A Planned with new funding DOS46L Immune and COVID-19 rejuvenation, HIV (Roman Regimen) Completing IMPD stage (Q1 2023). First in Human dosing planned in late 2023 (Influenza vaccination of the elderly) DOS144D Oncology Pre-clinical studies in both stand alone protocols and in combination with check point
Platform - Sentcell® About Team Milestones Publications and Updates Contact Platform Pipeline Platform sMACs are large macromolecular complexes that are formed during the ageing of the T cells and possibly other cell types too Overview sMACs are large macromolecular complexes that are formed during the ageing of the T cells and possibly other cell types too. They consist of a set of cellular rheostats (sestrins), an energy sensor (the heterotrimer alpha, beta, gamma kinase AMPK), and three effector kinases (the mitogen activated protein kinases (MAPK): JNK, ERK and p38). While these three esse
Sentcell® About Team Milestones Publications and Updates Contact Platform Pipeline Live Better. Live Longer. Live Again. Achieve human rejuvenation. Similar to green technologies, where measures are implemented with a long-term outlook rather than an immediate short-term narrowed outcome, our compounds will respect the integrity of human physiology to improve healthspan, resulting in a consequent increase in human lifespan for all. About Pillars of ageing T cells are at the pinnacle of the ageing clock across all organs yet no T cell rejuvenating therapies exist. Sentcell fundamental medicine
Instagram Instagram Log In Sign Up Close Never miss a post from indypersian Sign up for Instagram to stay in the loop. Sign up Log in indypersian and indypersianpod More options indypersian Verified 26w . مارکو روبیو، وزیر امور خارجه آمریکا، در نشست خبری روز جمعه ۲۸ آذر، با تاکید بر اختلافات نهادینه آمریکا با جمهوری اسلامی، شکاف میان حکومت و مردم ایران را در جهان بیسابقه خواند. روبیو در پاسخ به پرسشی درباره لزوم اولویتبندی حقوق بشر و موضوع اعدامها در کنار مذاکرات هستهای، تاکید کرد که واشنگتن هیچ توهمی نسبت به ماهیت این رژیم ندارد. او با اشاره به میراث فرهنگی و تاریخی غنی ایرانیان، اظهار دا
Menstrual health innovation shortlist revealed Latest News Opinion Insight Events Newsletter sign up Awards entry Contact us Advertise Podcast Connect with us FemTech World Menstrual health innovation shortlist revealed Latest News Opinion Insight Events Newsletter sign up Awards entry Contact us Advertise Podcast News Menstrual health innovation shortlist revealed Published 1 month ago on May 19, 2026 By News Desk We are thrilled to announce the shortlist for the Menstrual Health Innovation Award at the third annual FemTech World Awards. This award, sponsored by Premom exists to celebrate the … me seller of ovulation tests in the country. Premom’s sponsorship of this award reflects a shared commitment to empowering women with better tools, better knowledge and better outcomes across every stage of their reproductive health journey. This year’s shortlist is a testament to the remarkable breadth of innovation happening across the femtech landscape, from wearable bioelectronics to mission-driven apps reaching underserved communities across the globe. Congra … h World Awards Up Next Three brain and mental health innovators shortlisted for award Don't Miss Abdominal obesity may lead to more severe menopause symptoms – study News Desk Continue Reading You may like Just 24 hours left to nominate your company of the year Enter the menopause innovation award before it’s too late Entries for the Femtech World AI Innovation Award close this Friday Nominate your brain and mental health innovators before it’s too late … tartup changing the future of women’s health? Just over two weeks left to submit your menstrual health innovation Click to comment Leave a Reply Cancel reply Your email address will not be published. Required fields are marked * Comment * Name * Email * Website Save my name, email, and website in this browser for the next time I comment. News Ovum secures US$4m in seed funding Published 10 hours ago on June 23, 2026 By News Desk Women’s health startup Ovum has raised US … merge with Breakthrough Victoria, also participated through its Alice Anderson Fund, which focuses on female founders. Amanda Andriano, founding partner at Admiralty Capital Group, said the gender health gap was a problem that should not be tolerated. She said: “Ovum combines mission, market timing and technical capability with an exceptional fo
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Key Speakers | Vaccines Influencers | Vaccines Researchers | Vaccines Meeting November | Vaccines Summit-2026 Boston November --> Venue Boston Marriott Peabody, MA Dates November 16-18, 2026 Call +1-659-226-7797 --> Home Home Page 01 Home Page 02 Home Page 03 Header Styles Header Style 01 Header Style 02 Header Style 03 --> About About Vaccines Summit-2026 Vaccines Summit-2024 Vaccines Summit-2023 Vaccines Summit-2022 Vaccines Summit-2021 2023 Photo Gallery Contact Pages About About Us Buy Ticket Gallery Testimonials Comming Soon Schedule Schedule 01 Schedule 02 Schedule 03 Schedule Detail FAQ … 18, 2026 Dates [email protected] Mail to us +1-659-226-7797 Call Contact Us Submit Now Boston Marriott Peabody, MA Venue November 16-18, 2026 Dates [email protected] Mail to us +1-659-226-7797 Call Speakers Home Speakers Our SPEAKERS Speakers who are experts in their fields Rino Rappuoli, Ph.D. Scientific Director of the Biotecnopolo di Siena Foundation, Italy --> Andrew Pollard, FRCPCH, FMedSci, FRS Director, Oxford Vaccine Group Sanjay Gurunathan, M.D. Senior Vice P
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Contact - Sentcell® About Team Milestones Publications and Updates Contact Platform Pipeline Contact We always welcome enthusiastic and passionate people that share our curiosity and interest for fundamental biology Mails Connect with ®Sentcell [email protected] Careers at ®Sentcell [email protected] For investors and business partnerships [email protected] Contact Us Name * Email * Subject * Message * reCAPTCHA If you are human, leave this field blank. Send Platform Pipeline About Team Milestones Publications and Updates Headquarter 607 Sloane Avenue SW3 3EL, London England Uni
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Disruptors of sestrin-MAPK interactions rejuvenate T cells and expand TCR specificity | bioRxiv Skip to main content Home About Submit ALERTS / RSS Search for this keyword Advanced Search New Results Disruptors of sestrin-MAPK interactions rejuvenate T cells and expand TCR specificity Alessio Lanna , Clara D’Ambra , Federica Rinaldi , Luisa Chocarro , Manuel Delpero , Melania Capitani , Michael Karin doi: https://doi.org/10.1101/2024.05.17.594698 Alessio Lanna 1 Sentcell UK laboratories, IRCSS Fondazione Santa Lucia , Rome. Italy 2 University College London, Division of Medicine , London. Unit
A Preprint Claiming Exceptional Extension of Life in Mice via a Telomere Transfer Mechanism – Fight Aging! Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging! Do you want to live a longer life in good health? Simple practices can make some difference, such as exercise or calorie restriction. But over the long haul all that really matters is progress in medicine: building new classes of therapy to repair and reverse the known root causes of aging. The sooner these treatments arrive, the more lives will be saved. Find out how to h … Living Longer Read the Fight Aging! FAQ Sign up for the Fight Aging! Newsletter Fund Meaningful Aging Research Services Longevity Industry Consulting How to Start a Longevity Biotech Company The Root Causes of Aging Aging is Caused by Damage Accumulating Cross-Links Buildup of Amyloid Between Cells The Failing Adaptive Immune System The Failing Innate Immune System Declining Lysosomal Function Mitochondrial DNA Damage Nuclear DNA Damage Buildup of Senescent Cells Archives and … Feed RSS Comments Feed Using the Fight Aging! Content Feeds Required Reading A Proposal to Accelerate Progress Calorie Restriction and Longevity Cryonics, the Necessary Backup Plan How to Argue for Longevity Science The Odds of Human Longevity Mutations The Need For Activism and Advocacy Nuanced Opposition to the FDA Potential Gene Therapy Targets Predicting the First Rejuvenation Therapies Self-Experiment to Fight Aging! SENS: Bringing an End to Aging Stem Cells and Regener … ht Aging!. Home | FAQ | Fund Research | Services | Investing | Therapies | Newsletter | Archives | Press Room | Resources | About Read our terms and conditions and privacy poli
Elation Health acquires EHR startup Aster Latest News Opinion Insight Events Newsletter sign up Awards entry Contact us Advertise Podcast Connect with us FemTech World Elation Health acquires EHR startup Aster Latest News Opinion Insight Events Newsletter sign up Awards entry Contact us Advertise Podcast News Elation Health acquires EHR startup Aster Published 3 weeks ago on June 5, 2026 By News Desk Elation Health has acquired Aster, a women’s health EHR startup created by sisters Fifi Kara and Dr Lailah Kara-Newton. The deal, announced on 3 June 2026, will see Aster’s team join Elation Healt … merge with Breakthrough Victoria, also participated through its Alice Anderson Fund, which focuses on female founders. Amanda Andriano, founding partner at Admiralty Capital Group, said the gender health gap was a problem that should not be tolerated. She said: “Ovum combines mission, market timing and technical capability with an exceptional founder uniquely positioned to lead this movement, and we believe that creates the foundation for a company of global significance.” T … ealed News 4 weeks ago Three menopause innovators shortlisted for Femtech World Award Copyright © 2025 Aspect Health Media Ltd. All Rights Reserved. We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept All”, you consent to the use of ALL the cookies. However, you may visit "Cookie Settings" to provide a controlled consent. Cookie Settings Accept All Manage consent Close Privacy Overview T
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WO2023119337A1 - Sestrin-mapk complex inhibitors - Google Patents WO2023119337A1 - Sestrin-mapk complex inhibitors - Google Patents Sestrin-mapk complex inhibitors Download PDF Info Publication number WO2023119337A1 WO2023119337A1 PCT/IT2021/000059 IT2021000059W WO2023119337A1 WO 2023119337 A1 WO2023119337 A1 WO 2023119337A1 IT 2021000059 W IT2021000059 W IT 2021000059W WO 2023119337 A1 WO2023119337 A1 WO 2023119337A1 Authority WO WIPO (PCT) Prior art keywords analogue derivative sestrin cyclic polypeptide amino acid Prior art date 2021-12-24 Legal status (The legal status is an assumption and … is and makes no representation as to the accuracy of the status listed.) Ceased Application number PCT/IT2021/000059 Other languages French ( fr ) Inventor Alessio LANNA Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) Sentcell Ltd Original Assignee Sentcell Ltd Priority date (The priority date is an assumption and is not a legal conclusion. Google has n … sted.) 2021-12-24 Filing date 2021-12-24 Publication date 2023-06-29 2021-12-24 Application filed by Sentcell Ltd filed Critical Sentcell Ltd 2021-12-24 Priority to AU2021480402A priority Critical patent/AU2021480402A1/en 2021-12-24 Priority to EP21854888.1A priority patent/EP4452290A1/en 2021-12-24 Priority to CN202180105211.XA priority patent/CN118434433A/en 2021-12-24 Priority to KR1020247025066A priority patent/KR20240144153A/en 2021-12-24 Priority to JP2024538274A priori … mapk complex inhibitors Ceased WO2023119337A1 ( en ) Priority Applications (10) Application Number Priority Date Filing Date Title AU2021480402A AU2021480402A1 ( en ) 2021-12-24 2021-12-24 Sestrin-mapk complex inhibitors EP21854888.1A EP4452290A1 ( en ) 2021-12-24 2021-12-24 Sestrin-mapk complex inhibitors CN202180105211.XA CN118434433A ( en ) 2021-12-24 2021-12-24 Sestin-MAPK complex inhibitors KR1020247025066A KR20240144153A ( en ) 2021-12-24 2021-12-24 Sestrin-MAPK complex … 4 2021-12-24 Sestrin-mapk complex inhibitors Applications Claiming Priority (1) Application Number Priority Date Filing Date Title PCT/IT2021/000059 WO2023119337A1 ( en ) 2021-12-24 2021-12-24 Sestrin-mapk complex inhibitors Publications (1) Publication Number Publication Date WO2023119337A1 true WO2023119337A1 ( en ) 2023-06-29 Family ID=8044576
CD4⁺ T cells confer transplantable rejuvenation via Rivers of telomeres | bioRxiv Skip to main content Home About Submit ALERTS / RSS Search for this keyword Advanced Search New Results CD4⁺ T cells confer transplantable rejuvenation via Rivers of telomeres View ORCID Profile Alessio Lanna , Salvatore Valvo , Michael L. Dustin , Federica Rinaldi doi: https://doi.org/10.1101/2025.11.14.688504 Alessio Lanna 1 Sentcell UK laboratories, Tuscany Life Sciences, GSK Vaccine Campus , Siena. Italy 3 University College London, Division of Medicine , London. United Kingdom Find this author on Google Scho
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