C-1NZUorgan preservation, tissue preservation, organ banking
0-100 chain-logic scale · 15 dimensions · scored on public evidence
Advance biostasis and preservation research through a funded research consortium connected to the planned Biostasis Research Institute research centers.
Research consortium grant and matching-partner funding model led by founding teams of the planned research centers.
First research consortium grant awarded in 2020, with approximately $80 million expected from the National Science Foundation and matching partners.
Create a research institute and consortium infrastructure to advance cryopreservation and biostasis research.
Consensus-building, site selection, matching donation campaigns, and consortium grant applications to fund organ preservation and biostasis research centers.
In 2020, the first research consortium grant was awarded: ATP-Bio, with approximately $80 million expected from the National Science Foundation and matching partners.
OPA's earlier consensus-building and fundraising helped lay groundwork for the Biostasis Research Institute and ATP-Bio consortium funding.
Create dedicated research infrastructure for biostasis and cryopreservation research emerging from OPA's organ preservation consensus-building work.
Institute planning, site selection, matching donation campaign, and consortium grant applications.
OPA began planning the Biostasis Research Institute in 2018 after a $2 million Bitcoin donation; consortium grant applications were submitted to NSF, Gates Foundation, MacArthur Foundation, and others.
Provide background materials and concept references to support organ and tissue banking research planning and education.
Distribution of curated background materials, technical PDFs, and a compendium of organ- and tissue-banking concepts.
The 2015 Compendium of Organ & Tissue Banking Concepts is listed among Organ Preservation Alliance publications/materials.
Provide curated concepts and background material to support organ and tissue banking research planning and education.
Compilation and distribution of organ- and tissue-banking concepts and technical background materials.
2015 compendium listed in Organ Preservation Alliance-related publications/materials.
Identify and organize the major scientific and technical challenges involved in complex tissue cryopreservation and organ banking.
Global summit proceedings and research agenda for complex tissue cryopreservation.
2016 publication of proceedings from the first global summit on complex tissue cryopreservation.
The supplied materials identify the proceedings as focused on grand challenges in organ banking; no intervention-specific results are supplied.
Identify scientific and technical barriers to complex tissue cryopreservation and organ banking.
Global summit proceedings and consensus-building around complex tissue cryopreservation challenges.
2016 proceedings publication from the first global summit on complex tissue cryopreservation.
Proceedings documented grand challenges for organ banking and complex tissue cryopreservation.
Identify grand challenges in complex tissue cryopreservation and organ banking.
Global summit and proceedings focused on complex tissue cryopreservation and organ banking.
Proceedings from the first global summit on complex tissue cryopreservation were published in 2016.
The proceedings documented challenges and priorities for complex tissue cryopreservation.
Support organ and tissue preservation researchers by curating relevant funding opportunities and application resources.
Compilation of grant opportunities, foundation support areas, deadlines, and application guidance relevant to organ and tissue preservation researchers.
MTEC profile describes grant and funding resource curation as an Organ Preservation Alliance activity.
Extend the preservation time of human organs and tissues outside the body to improve organ transplantation, regenerative medicine, drug discovery, and disease research.
Nonprofit research-catalysis program coordinating researchers, clinicians, advocacy organizations, academic institutions, science agencies, stakeholders, and media around biopreservation and organ/tissue preservation advances.
A 2017 Nature Biotechnology article described a coordinated effort and new preservation paradigm integrating multiple existing preservation approaches and newer technologies.
Extend the amount of time human organs and tissues can be preserved outside the body, with potential applications in transplantation, regenerative medicine, drug discovery, and disease research.
Coordinated research and field-building around biopreservation, organ preservation, tissue preservation, and organ banking technologies.
Publication of field-level analysis on the promise of organ and tissue preservation to transform medicine in 2017 and social, economic, and policy implications in 2018.
Publications describe unmet needs, logistical constraints in transplantation, and opportunities for coordinated preservation advances; no company-specific experimental efficacy results are supplied.
Define technical priorities and underfunded opportunities for organ banking and complex tissue preservation.
Technology roadmap and consensus-building effort drawing on organ and tissue banking concepts, preservation literature, and stakeholder input.
NSF-sponsored organ banking technology roadmap listed among Organ Preservation Alliance publications/materials.