Endogenous regenerative medicine discovery platform
exploratoryplatform · high · Mon Jan 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time)
Discover first-in-class medicines that repair and regenerate tissues and organs by controlling endogenous adult stem and progenitor cells.
Discovery approach using small molecules to selectively regulate endogenous adult stem and progenitor cells for controlled tissue repair.
Platform described on company site and supported by a 2024 retinal degeneration model publication.
In a mammalian retinal degeneration model, repeated intravitreal injections of a small molecule improved outer nuclear layer thickness and regenerated visual function as measured by ERG, visual acuity, and contrast sensitivity tests.