Niagen Plus injectable nicotinamide riboside safety program
phase 1drug program · high · Tue Apr 28 2026 00:00:00 GMT+0000 (Coordinated Universal Time)
Evaluate safety, tolerability, NAD+ blood-level effects, participant and clinician injection experience, and exploratory changes in fatigue, sleep, quality of life, inflammation markers, mitochondrial efficiency, and perceived skin appearance.
Randomized open-label clinical study of injectable Niagen Plus, an injectable form of nicotinamide riboside, delivered by subcutaneous or intramuscular injection at 50 mg or 100 mg, including in-clinic dosing followed by home self-injection through Day 100.
ClinicalTrials.gov record published 2025-10-01 for a 40-participant 100-day study; a 2026 medRxiv preliminary safety analysis reported two pilot clinical trials of injected NR.
In the preliminary safety analysis, injectable NR interventions were associated with some discomfort but were well tolerated, with no concerning safety signals; reductions in systolic blood pressure and hsCRP findings were described as requiring larger or hypothesis-generating follow-up.
TRU NIAGEN cognition, mood, and sleep study in older adults
exploratoryresearch program · high · Wed Jun 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time)
Assess effects of TRU NIAGEN nicotinamide riboside on cognitive function, mood, and sleep in men and women over 55 years of age.
Double-blind randomized crossover study comparing 300 mg/day and 1000 mg/day TRU NIAGEN with placebo.
ClinicalTrials.gov record published 2018-06-13; study sponsored by ChromaDex and managed by Midwest Center for Metabolic and Cardiovascular Research.
Niagen Bioscience NAD+ research and technology platform
exploratoryplatform · medium
Advance NAD+ science and healthy-aging applications through research-backed NAD-enhancement technology.
NAD+ research and technology platform involving Niagen nicotinamide riboside, patents, clinical studies, and global research collaborations.
Company site states Niagen Bioscience is the global leader in NAD+ research and technology with over 25 years of innovation.
Niagen / Tru Niagen nicotinamide riboside NAD+ enhancement
undisclosedconsumer product · high
Support healthy aging through NAD+ restoration using clinically researched Niagen nicotinamide riboside.
Oral dietary NAD+ precursor product based on Niagen nicotinamide riboside / NR Chloride, supported by patents, clinical studies, and research collaborations.
Niagen Bioscience describes Niagen and Tru Niagen as clinically researched NAD-enhancement solutions and states ChromaDex is now Niagen Bioscience.
