Lead neuroprotective enzyme mimetic compound
preclinicaldrug program · medium
Provide neuroprotection and potentially extend healthspan or lifespan by reducing oxidative and inflammatory injury.
Lead small molecule enzyme mimetic evaluated in double-blind, placebo-controlled animal studies and in wild-type mice dosed from middle age.
Reported preclinical animal evidence, including neuroprotective effects and lifespan extension in wild-type mice.
Described as neuroprotective in double-blind, placebo-controlled animal studies and as extending median lifespan in wild-type mice by around 15% when dosed from middle age.