Translational Initiative to Map Epigenetics in Sleep
exploratoryresearch program · high · Mon Apr 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time)
Explore relationships among chronotype, depression incidence, biological age, and whether working out-of-phase with chronotype is associated with depression and accelerated biological aging.
Clinical research study assessing chronotype, depression, and biological age/epigenetic aging endpoints.
ClinicalTrials.gov record published on 2024-04-01.
Translational Initiative to Map Epigenetics in Aging
exploratoryresearch program · high · Wed Mar 08 2023 00:00:00 GMT+0000 (Coordinated Universal Time)
Advance understanding of connections between epigenetics, lifestyle, demographics, health, and aging.
Clinical research study using epigenetic aging measurements and participant lifestyle/demographic/health data.
ClinicalTrials.gov record published on 2023-03-08.
Epigenetic Aging and NAD+ Biomarker Correlation Study
exploratoryresearch program · high · Thu Dec 19 2019 00:00:00 GMT+0000 (Coordinated Universal Time)
Evaluate correlations between epigenetic aging measured by DNA methylation and NAD+ levels in healthy volunteers.
Single-center prospective study measuring DNA methylation-based epigenetic aging and NAD+ levels.
ClinicalTrials.gov record published on 2019-12-19.
EH301 for ALS
undiscloseddrug program · medium · Sun Jan 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time)
Evaluate efficacy and tolerability of EH301 in patients with amyotrophic lateral sclerosis.
Randomized placebo-controlled clinical trial with daily EH301 or placebo and active evaluation for 6 months; supplied related publication describes nicotinamide riboside, pterostilbene, and ibudilast effects in ALS mice.
ClinicalTrials.gov record published on 2017-01-01.
Supplied public record gives trial objective but no clinical results. Supplied publication abstract reports nicotinamide riboside, pterostilbene, and ibudilast protected motor neurons and extended survival in ALS mice.
Basis
exploratoryconsumer product · high
Support healthy aging via NAD+ precursor supplementation and related clinical research across aging, menopause transition symptoms, exercise metabolism, liver fat, elderly health, and trauma recovery contexts.
Daily oral nicotinamide riboside plus pterostilbene supplementation; clinical studies compare recommended-dose Basis or NRPT against placebo or baseline endpoints.
2026 publication reported an open-label pilot clinical trial of NRPT/Basis in women over 35 with menopause-transition symptoms.
The 2026 pilot reported significant decreases in frequency and magnitude of bloating, hot flashes, and poor sleep in the symptomatic group, plus increased E2/E1 ratio. Earlier supplied trials studied elderly subjects, HIIT performance, liver fat, and elderly trauma recovery.
Creatine+
undisclosedconsumer product · low
Consumer longevity supplement product listed by Elysium Health.
Product methodology not specified in supplied material beyond product listing.
Listed among Elysium Health products in supplied site analysis.
Format
undisclosedconsumer product · low
Consumer healthy-aging/longevity supplement product listed by Elysium Health.
Product methodology not specified in supplied material beyond product listing.
Listed among Elysium Health products in supplied site analysis.
Glaucoma Methods and Compositions Program
discontinueddrug program · medium
Develop methods and compositions for treating glaucoma.
Patent application covering glaucoma-related compositions, doses, and administration methods assigned to Elysium Health Inc.
US20200384004A1 patent application publication; supplied record lists application status as abandoned.
Index Biological Age Test
exploratorybiomarker · high
Measure biological age and rate of aging using DNA methylation/epigenetic clock methods.
Principal component-based epigenetic clock trained to predict PhenoAge; used to assess epigenetic age and rate of aging.
2024 Aging Cell publication used Index in older adults with mild cognitive impairment from the VITACOG study.
Elevated homocysteine was associated with increased rate of epigenetic aging, and Index showed normalization of accelerated epigenetic aging after homocysteine-lowering B-vitamin treatment.
Matter
undisclosedconsumer product · low
Consumer healthy-aging/longevity supplement product listed by Elysium Health.
Product methodology not specified in supplied material beyond product listing.
Listed among Elysium Health products in supplied site analysis.
Mosaic
undisclosedconsumer product · low
Consumer healthy-aging/longevity supplement product listed by Elysium Health.
Product methodology not specified in supplied material beyond product listing.
Listed among Elysium Health products in supplied site analysis.
NAD(P)(H) Catabolism Analytical Program
exploratoryplatform · medium
Define known and emerging NAD(H) catabolites and support analytical methods that characterize the full NAD(H) metabolome during NAD precursor use.
Review and analytical framework focused on NAD(H) precursor catabolism, metabolite profiles, recycling, and elimination.
2023 Nutrients review publication.
The review emphasized that NAD(H) precursor supplementation changes NAD(H) catabolism profiles and that catabolite distribution varies by precursor, species, and tissue, supporting broader analytical methods for the NAD(H) metabolome.
NRPT UVB Protection Program
preclinicalresearch program · high
Assess whether nicotinamide riboside and pterostilbene can inhibit UVB-induced inflammatory tissue swelling and immune suppression.
Mouse studies using nicotinamide riboside, pterostilbene, or both before UVB radiation exposure; endpoints included ear swelling and contact hypersensitivity immune-suppression models.
2024 publication in Photodermatology Photoimmunology & Photomedicine.
Combination nicotinamide riboside plus pterostilbene inhibited UVB-induced skin swelling more than either agent alone. Pterostilbene alone and the combination inhibited UVB-induced immune suppression in low- and high-dose models.
Senolytic Complex
undisclosedconsumer product · low
Consumer senolytic-oriented longevity supplement product listed by Elysium Health.
Product methodology not specified in supplied material beyond product listing.
Listed among Elysium Health products in supplied site analysis.
Signal
undisclosedconsumer product · low
Consumer healthy-aging/longevity supplement product listed by Elysium Health.
Product methodology not specified in supplied material beyond product listing.
Listed among Elysium Health products in supplied site analysis.
Vision
undisclosedconsumer product · low
Consumer healthy-aging/longevity supplement product listed by Elysium Health.
Product methodology not specified in supplied material beyond product listing.
Listed among Elysium Health products in supplied site analysis.
