XT-ViVo and TimeSeal kidney preservation system
undisclosedplatform · medium · Fri Mar 20 2026 00:00:00 GMT+0000 (Coordinated Universal Time)
Enable subzero preservation and transport of kidneys for transplantation for up to 5 days.
XT-ViVo preservation solution combined with the TimeSeal subzero preservation and transport system for organs at high subzero temperatures.
Company site states the XT-ViVo and TimeSeal solution stores kidneys for up to 5 days at high subzero temperatures for transplantation; 2026 public design records list X-Therma filings for cooling plates and packaging box parts.
Company-reported capability: kidney storage for up to 5 days at high subzero temperatures.
X-Therma biopreservation platform
undisclosedplatform · medium
Transform organs, engineered tissues, cells, gene therapies, and biologics into on-demand treatments through improved preservation, cryopreservation, and transport.
Biopreservation platform using antifreeze-molecule-inspired cryopreservation media and subzero preservation systems for organs, tissues, cells, and biologics.
Company site describes commercial product areas including DMSO-free cryopreservation media and subzero preservation and transport systems.
XT-Thrive DMSO-free cryopreservation media
exploratoryplatform · high
Provide a DMSO-free cryopreservation alternative for clinical-grade cell banking and cell therapy manufacturing, including mesenchymal stem cells and hematopoietic stem cells.
Chemically defined, DMSO-, protein-, and serum-free cryopreservation media inspired by natural antifreeze proteins; evaluated through post-thaw viability, recovery, proliferation, differentiation, genomic stability, and in vivo engraftment assays.
2026 publication evaluated XT-Thrive for mesenchymal stem cell master cell bank, working cell bank, and final product stages.
In MSCs, XT-Thrive maintained greater than 90% pre-freeze viability after 24-hour room-temperature holding, post-thaw viability above 85% at 6 hours, about 2.5-fold improved viable cell recovery in 3D microcarrier culture versus CS10, higher cumulative population doubling, higher CFU-F efficiency, enhanced osteogenic differentiation, and no reported compromise of karyotype integrity, telomere length, or in vivo safety. In human hematopoietic stem cells, XT-Thrive-A and XT-Thrive-B showed recovered stem cell numbers similar to DMSO with serum after mouse engraftment testing.
