Edifice Health Pre-Market trial
exploratoryresearch program · medium · Thu Oct 02 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
Collect paired clinical, functional, facial image, and iAge data to evaluate inflammatory aging measurement and digital prediction approaches.
Clinical study of 750 participants aged 20 to 90 with a subset having paired blood-derived iAge measurements and facial images.
Dataset used in the 2025 Healthy Selfie bioRxiv study.
Supported development of a facial-photo predictor of blood-derived iAge and individual inflammaging proteins including CXCL9, CXCL1, CCL11, TNFSF10, and IFNG.
Healthy Selfie digital iAge predictor
exploratoryconsumer product · medium · Thu Oct 02 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
Estimate inflammatory aging and blood inflammation from ordinary frontal facial photographs as a scalable, ultra-low-cost health assessment tool.
Digital model using pretrained facial image embeddings plus age, sex, and other metadata to predict blood-derived iAge and inflammaging proteins.
2025 bioRxiv preprint using data from the Edifice Health Pre-Market trial of 750 participants and external validation on about 100,000 images.
Photo-predicted iAge correlated with blood iAge at r = 0.536; increased iAge acceleration classification accuracy was 66.39%, sensitivity 65.61%, and specificity 67.24%.
Allergy inflammatory health program
undisclosedresearch program · low
Apply inflammatory health monitoring to allergy-related immune or inflammatory status.
Not specified beyond inflammatory biomarkers, omics, and AI-based inflammatory health monitoring.
Allergy listed in the company's pipeline.
Cancer immunology inflammatory aging program
exploratoryresearch program · medium
Apply inflammatory age-clock-related genes and inflammatory aging clocks to cancer prognosis, immunity markers, patient subtype characterization, and survival prediction.
Multi-omics cancer analysis and inflammatory aging clock modeling, including glioblastoma overall survival prediction.
2025 cancer-focused publications listed in the supplied publication set.
Reported focus areas include pan-cancer prognostic and immunity markers and glioblastoma subtype and overall survival prediction.
Cardiovascular inflammatory aging program
exploratoryresearch program · medium
Use inflammatory aging and immune-health biomarkers to assess cardiovascular aging and cardiovascular disease risk.
Inflammatory aging clock and inflammatory biomarker analysis, including JAK-STAT signaling and cardiovascular risk measures.
Cardiovascular Disease listed in the company's pipeline; iAge publication reports tracking cardiovascular aging.
The iAge clock is reported to track cardiovascular aging; prior listed research connects defective JAK-STAT signaling with chronic inflammation and cardiovascular risk in aging humans.
COVID-19 disease severity inflammatory health program
undisclosedresearch program · low
Assess or predict COVID-19 disease severity using inflammatory health markers.
Not specified beyond inflammatory biomarkers, omics, and AI-based inflammatory health monitoring.
COVID-19 Disease Severity listed in the company's pipeline.
Frailty inflammatory aging program
exploratoryresearch program · medium
Use inflammatory aging biomarkers to assess frailty and age-related functional decline.
Inflammatory aging clock analysis based on immune and inflammatory biomarkers.
Frailty listed in the company's pipeline; iAge publication reports tracking frailty.
The iAge clock is reported to track frailty, multimorbidity, and immunosenescence.
Inflammatory Age test
undisclosedbiomarker · high
Measure and monitor systemic chronic inflammation to support early detection, prevention, and management of age-related health risks.
Blood-based inflammatory health monitoring test derived from NIH-funded Stanford 1,000 Immunomes research using omics platforms, inflammatory biomarkers, and artificial intelligence.
Offered through clinic and physician partnerships as an inflammatory health monitoring test; listed as the company's core product/science platform.
The iAge inflammatory aging clock is reported to track multimorbidity, immunosenescence, frailty, cardiovascular aging, and all-cause mortality risk.
Intrinsic Capacity blood-based epigenetic clock
exploratorybiomarker · high
Predict mortality and characterize intrinsic capacity using a blood-based epigenetic aging measure associated with clinical, immunological, and lifestyle factors.
Blood-based epigenetic clock linked to inflammatory and immunological measures.
2025 publication listed on Edifice Health's site.
Reported to predict mortality and associate with clinical, immunological, and lifestyle factors.
Neurodegenerative disease inflammatory aging program
undisclosedresearch program · low
Apply inflammatory health monitoring to neurodegenerative disease risk or biology.
Not specified beyond inflammatory biomarkers, omics, and AI-based inflammatory health monitoring.
Neurodegenerative Disease listed in the company's pipeline.
Oat beta-glucan iAge intervention study
exploratoryresearch program · medium
Evaluate whether an oat product providing 3 g beta-glucan can reduce systemic chronic inflammation as measured by iAge in adults at cardiovascular disease risk.
Secondary measurement of serum samples from a placebo-controlled randomized clinical trial comparing oat product with rice control, using iAge as an inflammatory aging endpoint.
2022 Nutrients publication.
In participants with elevated baseline iAge, the oat product lowered iAge as early as two weeks post-treatment; the effect was largely driven by decreased Eotaxin-1.
