How we fight death
Where exactly are the bottlenecks?
The decision this question informs
Put effort where it unlocks the next step
Describe the chain from an idea to a useful capability. Identify the dependency that currently prevents the next step, and distinguish it from the other unfinished work.
What should happen next?
Unresolved: Is progress waiting on knowledge, a tool, execution capacity, resources or a decision outside the laboratory?
Next work: Name the blocked step, what it depends on, and the observable condition under which it could proceed.
What would change the direction: If removing the suspected obstacle does not allow the next step, revise the dependency map instead of repeating the same intervention.
Proposed agenda, not a statement that a study is underway.
Then the priority changes: More execution of the same plan will not resolve the missing explanation.
What this does not establish: A gap in the current record is not proof that nobody has studied it.
Continue the reasoning