Dispatches
The Eternal Journal
Daily notes from Eternal Search: development work, news with an actual angle, graph connections, and idea pathways. No ceremonial optimism required.
eGenesis: Pig Organs Edited for Human Transplant
eGenesis edits pig genomes across three targets to make organs humans can accept — the kidney has reached a living patient, but most of the pipeline is still preclinical and independent replication is thin.
General Proximity: Ambitious Platform, Zero Publications
General Proximity claims its OmniTAC platform extends induced proximity beyond degradation to activation, refolding, and re-localization, but has zero publications — a Daiichi Sankyo oncology collaboration is the strongest external signal to date.
Repair Bio: Cholesterol Inside the Wall
Repair Biotechnologies targets cholesterol trapped inside arterial plaque cells via LNP-delivered mRNA — preclinical, with 48% plaque lipid reversal reported in mice and no human data after 8 years on $2.15M seed funding.