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874 grants · 19 open · 435 companies · 2640 concepts874 / 19 / 435 / 2640
COMPANIESCompanies rated · 435 (no change)PROJECTSProjects rated · 70 (no change)CATALOGUE874 grants in catalogue · 19 open right nowPOWERED BYOpen Longevity · 501(c)(3) · Sherman Oaks, CACOMPANIESCompanies rated · 435 (no change)PROJECTSProjects rated · 70 (no change)CATALOGUE874 grants in catalogue · 19 open right nowPOWERED BYOpen Longevity · 501(c)(3) · Sherman Oaks, CA

Bryan Johnson

Johnson made longevity louder by turning his own protocol into media, a Don’t Die campaign, and an Rx platform. The hard evidence for field-building or scientific impact is thin.

40 / 100self-experimenterpopulariserentrepreneur@bryan_johnsonScoring AI engine · v0.4.0
Role
self-experimenterhigh confidence

This is the clearest channel in the record: public protocols, public prescriptions he personally uses, and ongoing n-of-1 testing. Delete the self-experiment and most of the longevity footprint described here collapses with it.

Bryan Johnson raised $60M for Blueprint. | Nate Matherson

also: populariser, entrepreneur, investor

Dimension breakdown

This score rates longevity commitment only. The role tags above — scientist, investor, and the rest — say what this person is; we don't score those separately.

Evidence is still sparse for this hero. Scores are shown with low-confidence warnings until more source material is harvested.

Future vision

8.0/ 10

Bryan Johnson has a highly public, durable, and ambitious future vision centered on defeating death and popularizing longevity through Blueprint and the Don't Die movement. The vision is clear and consistently messaged, with some concrete deployment pathways such as a longevity prescription platform, but the evidence provided is lighter on detailed scientific roadmap, timelines, risk handling, or directly endorsed mechanistic theories, which keeps it below field-defining maximum strength.

medium confidence

Scientific impact

2.0/ 10

Bryan Johnson has some direct scientific authorship evidence in cancer biology papers related to senescence and melanoma mechanisms, but the strongest citation-metrics block appears mismatched to another researcher and high-energy-physics work, so it cannot credibly support a high scientific-impact score for him. The remaining evidence supports limited direct scientific contribution rather than field-defining impact.

medium confidence

Capital deployed

3.0/ 10

The dimension applies because Bryan Johnson is presented as an entrepreneur/investor and longevity public figure, but the provided evidence contains no high- or medium-confidence disclosed investments, donations, or amounts deployed toward longevity. The strongest signals are institution-building claims around Blueprint/Don't Die and a self-published launch of a longevity prescription platform, which suggest some operational commitment but do not establish scale of capital deployed.

low confidence

Strategic taste

4.0/ 10

The evidence shows a coherent and high-risk strategy around translating Johnson's personal longevity protocol into consumer-facing products, medical access, partnerships, and media narrative. However, the record here is mostly self-published, very recent, and thin on early timing, counterfactual importance, field-level impact, or evidence that these choices opened paths others were not seeing.

low confidence

Field creation

2.0/ 10

The dimension applies, but the provided evidence only weakly supports field creation. The structured facts say Bryan Johnson founded one company, Minicircle, but it is listed as inactive and there is no supplied primary or independent corroboration showing that it created a durable organization, protocol, community, category, or funding path that made longevity work more possible for others.

low confidence

Bravery and conviction

5.0/ 10

The evidence supports a moderate bravery/conviction score primarily through public self-experimentation and visibility: Johnson publicly ties a longevity prescription platform to medications he says he personally uses, and presents a broad anti-death/longevity stance publicly. However, the supplied evidence does not substantiate stronger forms such as major career sacrifice, large relative financial risk, sustained conviction under serious criticism, or a clearly documented contrarian stand against mainstream opposition.

medium confidence

Multiplier effect

4.0/ 10

The dimension applies: the evidence suggests Johnson is trying to create second-order leverage through a longevity Rx platform, health-product partnerships, and media/cultural distribution. However, the concrete multiplier achievements are supported almost entirely by self-published X posts, with little independent or primary corroboration of actual talent attraction, capital mobilization, policy attention, durable collaborators, or follow-on projects. Under the independence gate, this cannot justify a score above 5.

low confidence
Vision

Destination

focusing on slowing aging and maintaining overall health rather than on performance or muscle gain

[S1] High 2026

We might be the first generation that doesn’t die.

[S2] High 2026

'My ultimate goal? Don't die': Bryan Johnson on his controversial plan to live for ever

[S3] High 2023

Conquering death will be humanity’s greatest achievement.

[S4] High

So, I decided that I wanted to work on one of those two things—either build superintelligence, or work on Don’t Die.

[S5] High

When we started Blueprint, we had the goal to measure every organ of the body, including skin, and slow its speed of aging and reverse the aging damage.

[S6] High

Conquering death will be humanity’s greatest achievement.

[S7] High

Path

No canonical quotes yet.

Strategy

Build and promote consumer-facing longevity platforms that combine personal protocol transparency, prescription access, and health-product partnerships around a broad anti-death thesis.

Johnson’s strategy appears centered on turning his personal longevity protocol into public-facing products and media, including a newly launched longevity Rx platform with prescriptions he says he personally uses [S3]. The platform emphasizes medical access through licensed doctors and pharmacies, suggesting an operating model that blends consumer demand with regulated clinical fulfillment [S3]. He also signals a partnership channel for female business owners with health products, reviewed by a science team, which points to ecosystem-building around longevity and health commerce [S1]. His public profile frames the mission at maximum ambition: conquering death as a human achievement [S5]. The Netflix-linked “don’t die” campaign indicates that media and cultural narrative are part of the distribution strategy, not separate from the longevity thesis [S4].

UnknownHighLongevity MedicinePrescription AccessWomen'S Health AwarenessConsumer Health ProductsAnti-Aging ProtocolsLA

Notable bets

MinicircleFounded company indicates a strategy of building longevity-related organizations rather than only funding external efforts.
Longevity Rx platform2026 · Launched a platform offering prescriptions he says he personally uses, translating personal longevity practices into a consumer medical access product.
medicine.immortals.com2026 · Promotes a dedicated medicine destination tied to the longevity Rx launch, suggesting platformization of longevity interventions.
Portfolio

Investments

Donations

No public rows yet.

Organizations founded

KernelCompany · Founder · 2016
KernelCompany · Founder · 2016
Scientific output
h-index93
Citations-
Papers3
Trials0
Bravery and conviction
Belief evolution
He later founded OS Fund and Kernel, and became a prominent longevity public figure through Blueprint and the Don't Die movement.Longevity path thesis · 2026 · He later founded OS Fund and Kernel, and became a prominent longevity public figure through Blueprint and the Don't Die movement.
Self-experimentation
Jet lag recovery protocolIntervention · Active · 2026 · Testing an eastbound flight jet lag recovery protocol using slow release caffeine in the morning and melatonin before bed.
Live until 2140Other · Active · 2025 · Publicly stated desire to live until the year 2140.
HBOT protocolIntervention · Active · 2024 · Started a hyperbaric oxygen therapy protocol of 60 sessions over 12 weeks at 2 atmospheres with 100% oxygen via face-mask.
HBOT protocolIntervention · Concluded · 2024 · Started a hyperbaric oxygen therapy protocol consisting of 60 sessions over 12 weeks.
Mesenchymal Stem Cells (MSCs)Stem Cell · Concluded · 2024 · Trialed young Swedish bone-derived mesenchymal stem cells injected into knees, hips, and shoulders.
Mesenchymal Stem Cells (MSCs)Stem Cell · Concluded · 2024 · Received 300 million young Swedish bone-derived mesenchymal stem cells injected into his knees, hips, and shoulders.
Follistatin gene therapyGene Therapy · Concluded · 2023 · Received a first gene therapy intervention using follistatin.
Project BlueprintOther · Unknown · 2021 · An anti-aging attempt announced by Bryan Johnson.
Project BlueprintOther · Unknown · 2021 · An anti-aging attempt publicly announced by Bryan Johnson.
Longevity Rx prescriptions platformIntervention · Active · Publicly stated that his longevity Rx platform includes prescriptions he personally uses: Tadalafil, Metformin, Oral Minoxidil, Tretinoin, Estradiol, and Acarbose.
Connections

Companies

MinicircleFounder · Bryan Johnson, Founder of Project Blueprint

Collaborators and lineage

licensed doctors and pharmaciesCollaborator · The longevity Rx platform is described as working with licensed doctors and pharmacies to provide prescription access.
science teamCollaborator · A post invites female business owners with health products to email for the science team to review partnership opportunities.
Criticisms