Hurdle

diagnostics, multi-omics biomarkers, AI

diagnostics

hurdle.bio·London, United Kingdom·

01Overview 02People 03Projects 04Concepts 05Patents 06Public records 07Belief evolution

Plate C · C-QCH3

Summary · Eternal Search editorial

Hurdle diagnostics, multi-omics biomarkers, AI

Hurdle offers an integrated diagnostics platform for healthcare providers, telehealth companies, consumer healthcare, clinical research organisations, and employee benefits consultants. Its services include biomarker R&D, sample collection kits, lab testing, logistics and fulfilment, partner dashboards, and digital patient experiences. The site describes AI-driven biomarker discovery and validation using multi-modal data for precision medicine.

The published score reflects a curated read of public evidence across 16 dimensions. Each dimension below shows the rationale we used. Disagree with a reading? Tell us where we are wrong →

Plate C·01 · Scientific profile

All 16 dimensions
on the record.

Composite12

Chain scale100 pts

Dimensions16

Plate C·02 · Where it sits among peers

Score vs. proximity
to longevity goals.

Higher up = higher Eternal Search score. Further right = closer to achieving real longevity outcomes (early mechanism → translational → near-term readout). Bubble size = capital deployed. Watch for MISMATCHES: big bubbles on the left are well-capitalized but far from goals; small bubbles on the right are doing more with less.

Reading

Hurdle — Far from goals · Bottom quartile. Derived deterministically from 3 extracted project(s). Most-advanced status: undisclosed. Band: far. Modifiers: +5 depth (2 programs at undisclosed).…

Source: Deterministic

At a glance

Webhurdle.bio

HQLondon, United Kingdom

Publications

80 on file

012026Design and rationale of the pERSonalized cardIovascuLar dIsease prEvention, treatmeNt, and CarE (RESILIENCE) study.Contemporary clinical trials→022026Multimodal imaging reveals a lysosomal drug reservoir that drives heterogeneous distribution of PARP inhibitors.Nature communications→032026Systematic analysis of the type VII secretion system in Streptococcus ...biorxiv→042026Climate-Informed Deep Learning for Spatio-Temporal Forecasting of ...medrxiv→052026More Short Term Pain in Noncemented Total Knee Arthroplasty: A Matched Cohort Analysis.The Journal of the American Academy of Orthopaedic Surgeons→062025A novel framework to build saliva-based DNA methylation biomarkers: Quantifying systemic chronic inflammation as a case study.Aging cell→072025Testing the Effectiveness of a Commercially Sold Probiotic on Restoring the Gut Microbiota of Honey Bees: a Field Study.Probiotics and antimicrobial proteins→082025An exploratory analysis of bezisterim treatment associated with decreased biological age acceleration, and improved clinical measure and biomarker changes in mild-to-moderate probable Alzheimer's disease.Frontiers in neuroscience→092025Targeting unique ligand binding domain structural features downregulates DKK1 in Y537S ESR1 mutant breast cancer cells.Breast cancer research : BCR→102025The impact of artificial intelligence on biomarker discovery.Emerging topics in life sciences→112025Validation and standardization of the content of three di-caffeoylquinic acid in Korean Ligularia fischeri by region of origin.Scientific reports→122025Annual Blood Tests Are an Acceptable form of Surveillance to Supplement Colonoscopies for Colorectal Cancer.Digestive diseases and sciences→132025Correction: An exploratory analysis of bezisterim treatment associated with decreased biological age acceleration, and improved clinical measure and biomarker changes in mild-to-moderate probable Alzheimer's disease.Frontiers in neuroscience→142024A combination nutritional supplement reduces DNA methylation age only in older adults with a raised epigenetic age.GeroScience→152024[Not Available].Acta pharmaceutica Sinica. B→162024CD9 shapes glucocorticoid sensitivity in pediatric B-cell precursor acute lymphoblastic leukemia.Haematologica→172024COVERT: A classless approach to generating balanced datasets for process modelling.ISA transactions→182024Multi-qubit gates and Schrödinger cat states in an optical clock.Nature→192024Gut Bacterial Metabolites from Tryptophan and Phenylalanine Induce Melatonin Synthesis and Extend Sleep Duration in Mice.ACS omega→202024Protective Effects of Purple Corn (Zea mays L.) Byproduct Extract on Blue Light-Induced Retinal Damage in A2E-Accumulated ARPE-19 Cells.Preventive nutrition and food science→212024Targeting Unique Ligand Binding Domain Structural Features Downregulates DKK1 in Y537S ESR1 Mutant Breast Cancer Cells.Research square→222024The Skin Histopathology of Pro- and Parabiotics in a Mouse Model of Atopic Dermatitis.Nutrients→232024Targeting Unique Ligand Binding Domain Structural Features Downregulates DKK1 in Y537S ESR1 Mutant Breast Cancer Cells.bioRxiv : the preprint server for biology→242023Using Natural Language Processing and Machine Learning to Identify Internal Medicine-Pediatrics Residency Values in Applications.Academic medicine : journal of the Association of American Medical Colleges→252023Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth.bioRxiv : the preprint server for biology→262023A novel framework to build saliva-based DNA methylation biomarkersbiorxiv→272023Targeting PPAR-gamma counteracts tumour adaptation to immune-checkpoint blockade in hepatocellular carcinoma.Gut→282023Detection of Single Cancer Cell Multidrug Resistance With Single Cell Bioanalyzer.Technology in cancer research & treatment→292023Detection of Single Non-small Cell Lung Cancer Cell Multidrug Resistance with Single-Cell Bioanalyzer.Methods in molecular biology (Clifton, N.J.)→302022Warming in the land of the midnight sun: breeding birds may suffer greater heat stress at high- versus low-Arctic sites.Proceedings. Biological sciences→312022Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming.Aging cell→322022Multi-omic rejuvenation of human cells by maturation phase transient reprogramming.eLife→332021Patient Falls, Nurse Communication, and Nurse Hourly Rounding in Acute Care: Linking Patient Experience and Outcomes.Journal of public health management and practice : JPHMP→342021Disparities in COVID-19 vaccine hesitancy among Los Angeles County adults after vaccine authorization.Preventive medicine reports→352019A two-site survey of medical center personnel's willingness to share clinical data for research: implications for reproducible health NLP research.BMC medical informatics and decision making→362019Multiple Sclerosis at Home Access (MAHA): An Initiative to Improve Care in the Community.International journal of MS care→372019MSqRob takes the missing hurdle: uniting intensity- and count ...biorxiv→382019Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.Genome biology→392019Screening for genes that accelerate the epigenetic ageing clock in ...biorxiv→402018Trie-based rule processing for clinical NLP: A use-case study of n-trie, making the ConText algorithm more efficient and scalable.Journal of biomedical informatics→412017Adherence to disease-modifying therapies for multiple sclerosis and subsequent hospitalizations.Pharmacoepidemiology and drug safety→422017P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering ...biorxiv→432017HBVcircle: A novel tool to investigate hepatitis B virus covalently closed circular DNA.Journal of hepatology→442017The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression.Nature communications→452017Coagulation after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a retrospective cohort analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie→462017An Innovative Method for Monitoring Food Quality and the Healthfulness of Consumers' Grocery Purchases.Nutrients→472016A Rapid Systematic Review and Meta-Analysis of the Efficacy of Slaughter and Processing Interventions to Control Non-Typhoidal Salmonella in Beef and Pork.Journal of food protection→482016Ultrasound-Guided Spinal Procedures for Pain: A Review.Physical medicine and rehabilitation clinics of North America→492016A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance.Scientific reports→502016Delivery of RNAi Therapeutics to the Airways-From Bench to Bedside.Molecules (Basel, Switzerland)→512015An Analysis of Information Technology Adoption by IRBs of Large Academic Medical Centers in the United States.Journal of empirical research on human research ethics : JERHRE→522015Reflections on the Press Service for RSNA 1961-1969.Radiology→532014A comparison of intravenous and intradiscal delivery of multipotential stem cells on the healing of injured intervertebral disk.Journal of orthopaedic research : official publication of the Orthopaedic Research Society→542014Action of nitroheterocyclic drugs against Clostridium difficile.International journal of antimicrobial agents→552013Document Sublanguage Clustering to Detect Medical Specialty in Cross-institutional Clinical Texts.Proceedings of the ACM ... International Workshop on Data and Text Mining in Biomedical Informatics. ACM International Workshop on Data and Text Mining in Biomedical Informatics→562013Identifying clinical/translational research cohorts: ascertainment via querying an integrated multi-source database.Journal of the American Medical Informatics Association : JAMIA→572012Increased oxygen consumption and OXPHOS potential in superhealer mesenchymal stem cells.Cell regeneration (London, England)→582012Locoregional anesthesia for endovascular aneurysm repair.Journal of vascular surgery→592011The identification and management of ADHD offenders within the criminal justice system: a consensus statement from the UK Adult ADHD Network and criminal justice agencies.BMC psychiatry→602011Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections.Nature reviews. Microbiology→612011Benchmarking membrane protein detergent stability for improving throughput of high-resolution X-ray structures.Structure (London, England : 1993)→622010Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice.PloS one→632009Lee Theros.Journal of the American College of Radiology : JACR→642009Economic evaluation of etanercept in the management of chronic plaque psoriasis.The British journal of dermatology→652009Principles, approaches, and challenges for predicting protein aggregation rates and shelf life.Journal of pharmaceutical sciences→662009Edward Leland Jenkinson.Journal of the American College of Radiology : JACR→672009The Maxfield family.Journal of the American College of Radiology : JACR→682008Cost-effectiveness of heptavalent conjugate pneumococcal vaccine (Prevenar) in Germany: considering a high-risk population and herd immunity effects.The European journal of health economics : HEPAC : health economics in prevention and care→692008Selective killing of HIV-1-positive macrophages and T cells by the Rev-dependent lentivirus carrying anthrolysin O from Bacillus anthracis.Retrovirology→702008Cost-effectiveness of left ventricular-assist devices in end-stage heart failure.Expert review of cardiovascular therapy→712008A cost-minimisation analysis comparing moxifloxacin with levofloxacin plus ceftriaxone for the treatment of patients with community-acquired pneumonia in Germany: results from the MOTIV trial.Current medical research and opinion→722007A code of professional ethical conduct for the American Medical Informatics Association: an AMIA Board of Directors approved white paper.Journal of the American Medical Informatics Association : JAMIA→732007Ultrasound-guided blockade of the lateral femoral cutaneous nerve: technical description and review of 10 cases.Archives of physical medicine and rehabilitation→742006The current and future burden and cost of overactive bladder in five European countries.European urology→752006Costs of chemotherapy for indolent follicular non-Hodgkin's lymphoma in the UK: an observational study.Acta haematologica→762006The cost-effectiveness of lamotrigine in the maintenance treatment of adults with bipolar I disorder.Journal of managed care pharmacy : JMCP→772005Cost of home palliative care compared with conventional hospital care for patients with haematological cancers in Greece.The European journal of health economics : HEPAC : health economics in prevention and care→782004An economic evaluation of the costs and benefits of heparin rationalisation in a hospital pharmacy.Pharmacy world & science : PWS→792004Cost-effectiveness of low-level heat wrap therapy for low back pain.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research→802003Financial and health costs of uncontrolled blood pressure in the United Kingdom.PharmacoEconomics→

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0-100 chain-logic scale · 15 dimensions · scored on public evidence

Hurdle

All 16 dimensionson the record.

Score vs. proximityto longevity goals.

Publications

Loading

All 16 dimensionson the record.

Score vs. proximityto longevity goals.

Publications

All 16 dimensions
on the record.

Score vs. proximity
to longevity goals.

All 16 dimensions
on the record.

Score vs. proximity
to longevity goals.